1261
The Flood / Re: What's your first name?
« on: September 26, 2016, 04:24:19 PM »Séamus.
No surprises, right.
top of tha mornin to ya
I'll give you an actual Irish saying;
Spoiler
This section allows you to view all posts made by this member. Note that you can only see posts made in areas you currently have access to. 1261
The Flood / Re: What's your first name?« on: September 26, 2016, 04:24:19 PM »Séamus. I'll give you an actual Irish saying; Spoiler 1262
The Flood / Re: What's your first name?« on: September 26, 2016, 02:32:26 PM »
Séamus.
No surprises, right. 1263
Serious / Re: Genetic Engineering, Pt. II - CRISPR & CAS9« on: September 26, 2016, 12:07:13 PM »There was an article published in 2015, and was mentioned late in the first video, by scientists in china who used CRISPR/Cas9 on tripronuclear (3PN) human zygotes to see if they could effectively repair a defective copy of a certain gene. However, the frequency of homologous recombination of their supplied transcript was low, roughly 25% (off the top of my head). Is 25% success higher than what we're currently getting with ZFN or TALEN methods? If not, then the main advantage of CRISPR is saving time and funding to produce at least some results (I'm thinking a quick brute-force method over meticulous but productive). Quote I think the first video really over-glorifies the capabilities of CRISPR/Cas9 as it is now, but I am rather interested in its gene drive implications that appear to lead to "super-mendelian inheritance". There is also research into combining the sequence targeting capabilities of CRISPR with enzymatic domains of adenosine deaminases to create base editors that appear to have more effective use compared to the standard CRISPR/Cas9 system. I kinda got that vibe too from it, but if it's something that could be spectacular in it's infancy then it's worth waiting to see what comes of it as it's researched and tested more (particularly if the upfront cost is lower). Who knows, with gene-drive it could be possible to eradicate other diseases by targeting the parents without having to genetically alter a zygote/fetus during pregnancy and all the risks that brings (but I'm completely out of my element here, so I don't know how exactly that would work, if at all). 1264
The Flood / Re: literally the second taste of fall« on: September 25, 2016, 08:17:47 PM »So does it taste like cider does here, or is it like a runnier version of the filling of an apple pie?it's like apple juice but way thicker and more full Oh shit that does sound good. I'll have to put it on my America bucketlist whenever I get there. 1265
The Flood / Re: literally the second taste of fall« on: September 25, 2016, 08:10:40 PM »
So does it taste like cider does here, or is it like a runnier version of the filling of an apple pie?
(Come to think of it, ciders are pretty sweet compared to most beers) 1266
Serious / Re: Major study on gun ownership in the US« on: September 25, 2016, 12:54:07 PM »
Jesus christ. In what scenario does one person end up owning 140 guns?
Spoiler InB4 "found em" 1268
The Flood / Re: going to be a big party in my (student housing) neighborhood in the weekend« on: September 25, 2016, 09:08:01 AM »Update: didn't get some But did you have fun? That should be the priority, everything else is a bonus. Had an impromptu house party at mine on Thursday, ended up jumping the back garden fence over to next door and joined my neighbours in theirs. Two separate parties became a big one, and it was good. 1269
The Flood / Re: sep7 memories~« on: September 24, 2016, 07:47:49 PM »
Does it ever get updated? It's more of a historical archive than a recent article on bullshit, piss-taking, and memes.
1270
Gaming / Re: What makes a game fun for you?« on: September 23, 2016, 07:43:09 PM »
Immersion.
I can enjoy a good 20 minute match or even those 1 hour 2000 ticket servers of one BF4 map because of the sound, visuals, gameplay and the smoothness of things, but can't bear a 10 minute game of 2010's CoD nowadays because it hasn't changed since 2004 and you can see through the illusions clearly, not to mention the god-awful stories. Backstory stuff that's completely irrelevant to gameplay, but adds character to the story and constructs the universe beyond just what little you see of it (Examples include Deus Ex's E-books and personal computer logs, Elder scrolls' books and letters, and Fallout's terminal entries, notes, pre-war books, and exhausting every dialogue option possible past the "Yes, I'll do that thing for you"). Favourable art direction and design is also a factor, but that's totally down to opinion. I liked Borderland's cell-shading, Deus Ex's recent weird obsession with abstract polygonal installations... though not so much on the yellow tint, and GTA IV's "realistic (for the time) but grimy" approach, but it can be forgone in other games (Fallout 3/NV were far behind the graphical capabilities at the time and almost by release had aged badly, yet I consider them within my top 10 favourites). 1271
The Flood / Re: Anger as Churchill's home is turned into Hitler HQ for Transformers 5« on: September 23, 2016, 02:24:19 PM »
To be fair that house kinda fits with the whole pillars and statues thing goin' on;
1272
Serious / Re: Genetic Engineering, Pt. II - CRISPR & CAS9« on: September 23, 2016, 10:57:26 AM »
As promised, second vid is up and OP updated.
1273
Serious / Re: Trump and racism« on: September 22, 2016, 08:55:01 AM »I have a theory that Trump didn't really want to be president. He wanted to prove a point. When he started gaining momentum, he did his level best to disqualify himself. I don't think anyone is more surprised than Trump himself that he's still in this race.Why wouldn't he just drop out, then? You'd think holding racist views or spouting crazy rhetoric would do that too. And worse than just backing out. If he backed out early, the public would barely care (see: basically everyone from the UK PM "elections" except May). Now with his antics everybody from America to Antarctica has an opinion on him as his views have been pasted everywhere to see. You can always make more business partners, but if the majority of people have seen him as an asshole, business'll dry up quickly. 1274
Serious / Re: Death in the family...« on: September 21, 2016, 05:55:31 AM »like i said, no one i deeply cared about has died. i really cant be sad for someone ive never had a connection with, like you did with your loved one, so its hard to imagineNo idea, no one I actually cared for in my family has died at the moment. Grandma, I don't talk to her really, uncle, well I don't care really (just his life before and hidden details from his son), and a brain dead cousin, all died from what I remember. I can't really sympathize with what you're dealing with, but I never really felt sad for those deaths. All I said was, well, its bound to happen and we can only just remember them for the good they've caused. I too have the fortune to have no dead close relatives, yet. Most died before I was born (e.g. some Grandparents on both sides) and some I don't know all that well so hearing of their deth wouldn't phase me much, unless it was a particularly gruesome end. And to answer your question Deci, I've not a clue. I think if I thought about the time spent I might feel worse because I wouldn't be ble to revisit/re-live those moments, so I'd try to blank them. Sounds pretty cruel doing that to someone who's died recently that I cared about, but they won't care afterwards and I would have to cope somehow for the time being. 1275
Gaming / Re: What would you consider game of the decade?« on: September 20, 2016, 04:30:04 AM »1276
Gaming / Re: Fallout Megathread« on: September 17, 2016, 06:43:14 AM »
Turns out there's some extra dialogue from Virgil if you bring Strong along for the ride. I'll put it up later, but it involves...
Spoiler ...giving the reverse-FEV serum to make Virgil human again. Strong hated that. 1277
Gaming / Re: "It's impossible to have a worst game of all time nowadays."« on: September 16, 2016, 04:01:09 PM »
Only one person will ever play the worst game ever. It'll be the dev of some never heard "company" in a garage having a quick playtest and commenting "Man, this is shit".
1278
The Flood / Re: Introducing Sep7agon Bioshock Rapture Theme« on: September 16, 2016, 03:56:06 PM »Change the fourth value of rgba Yep...yep, there we go... Perfect. Spoiler Ok but seriously now it's this. Thanks! 1279
The Flood / Re: Introducing Sep7agon Bioshock Rapture Theme« on: September 16, 2016, 03:35:56 PM »
Aww sweet I've been meaning to change the background for ages but forgot the stylish stuff to install.
How the hell do I make the middle area (the bit with all the text and avatars, etc) less transparent? 1280
The Flood / Re: How much sleep do you get on average?« on: September 16, 2016, 06:31:10 AM »
6-7 on days where I need to be up for things (uni, etc), while on weekends without an alarm I usually catch up on lost sleep and get 11-13 hours.
Currently as I've got little to do and no alarm to set I get about 10 hours every night. 1281
Serious / Re: Shillary is coming to my university tomorrow« on: September 16, 2016, 05:14:15 AM »
-Shout "Sep7agon.net"
-Watch as CNN and whoever else wonder what it is -??? -Collect on Cheat's sudden new advertising revenue as millions of people come through here 1282
Gaming / Re: New Infinite Warfare trailer-Featuring: The King in the North« on: September 15, 2016, 04:38:26 PM »
Huh.
So it really is a Halo: Insurgency game. Spoiler "The Captain's place is at the bridge but I'mma have to do everything because the AI's retarded" 1283
Gaming / Re: Fallout Megathread« on: September 14, 2016, 09:03:04 PM »
There is something definitely wrong with my Fallout saves, or the game somehow.
It's like every second day I get an "unexpected error" that crashes it. Thankfully this happens so much I habitually quicksave every 5 minutes and have autosaves every 10. And this is with the damned perfect unaltered mod-free PS4 version. Also wrote-up a reply for something to do with pre-made voiced characters and their place (or lack of) in Fallout. Kinda long, but take a read: Spoiler Quote It seems to me that while previous characters had pasts, these were largely passive or independent from the player. Fallout 4 seems to have assumed some choices for the character already as if they had taken the initiative, which is a tad problematic depending on who you want your character to be. 1284
The Flood / Re: Does anyone here actually like Bob's Burgers?« on: September 14, 2016, 06:15:35 PM »
Tried watching it, felt like I had to forcefully plough through to enjoy small tidbits.
1285
Gaming / Re: 4K gaming. Does anyone care?« on: September 14, 2016, 06:04:04 PM »
It won't be relevant until we start getting mainstream 4K TV channels, e.g. BBC 4K.
And even then, it won't be a few years until everyone is on board. 1286
Gaming / Re: [EU - US - UK] All BF4 Expansions Free on PS Store.« on: September 14, 2016, 10:31:14 AM »I already posted this in the beta thread rrrreeeee BF4 isn't BF1 Beta Rrreeeeeee I'll edit the OP 1287
Gaming / [EU - US - UK] All BF4 Expansions Free on PS Store.« on: September 14, 2016, 07:04:28 AM »
(This should redirect you to the right region's store)
This applies to Current-Gens, so it's also on the Xbox1 (marketplace?). Oh, and on PC. So, if you've missed any during the weeks leading up to the BF1 Beta when they were free every week, here's your final chance now to claim them all at once. Premium edition, and the game itself still cost money. 1288
The Flood / Re: I've been reading a bunch of SCP and now I'm on edge and paranoid af« on: September 14, 2016, 06:39:53 AM »
I tried reading through them all, starting at 1.
I think I got to around 1000 before I lost interest. Some are good, most are interesting, but some are just meh. How some have [DATA EXPUNGED] or just black squares as it gets to some juicy bits is a bit of a tease. 1289
The Flood / Re: think about your most deeply held beliefs« on: September 14, 2016, 06:16:32 AM »
Probably.
Plenty of people disagree with me now and I'm still sticking to what I believe. 1290
The Flood / Re: God save our gracious memes« on: September 14, 2016, 06:12:13 AM »Reminds me, I should really look up the Irish Irish National Anthem. Turns out (after some wiki perusing), I don't know the Anthem. Everyone knows the rugby one (Ireland's Call), but the official one is Soldier's Song, something they don't tell you about at school. ...the fuck? |