some of the stuff in fullmetal alchemist is pretty disturbing. i think the entire "human transmutation" thing was a huge selling point for the moral questions the series asked.
ed and al trying to resurrect their mother with what's essentially blood magic... al loses his body and ed loses his arm and leg trying to pull it off. nina's father turning her into a chimera in order to further his research....
christ. for a shounen, fma had some heavy shit.