Long-term consequences of adolescent cannabis use

Mad Max | Mythic Invincible!
 
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http://journal.frontiersin.org/Journal/10.3389/fnins.2014.00361/abstract

Long-term marijuana use starting before 17 years of age leads to cognitive impairment and increased risk of psychotic disorders.
Quote
Marijuana is the most widely used illicit drug among adolescents and young adults. Unique cognitive, emotional, and social changes occur during this critical period of development from childhood into adulthood. The adolescent brain is in a state of transition and differs from the adult brain with respect to both anatomy (e.g., neuronal connections and morphology) and neurochemistry (e.g., dopamine, GABA, and glutamate). These changes are thought to support the emergence of adult cerebral processes and behaviors. The endocannabinoid system plays an important role in development by acting on synaptic plasticity, neuronal cell proliferation, migration, and differentiation. Delta-9-tetrahydrocanabinol (THC), the principal psychoactive component in marijuana, acts as a partial agonist of the cannabinoid type 1 receptor (CB1R). Thus, over-activation of the endocannabinoid system by chronic exposure to CB1R agonists (e.g., THC, CP-55,940, and WIN55,212-2) during adolescence can dramatically alter brain maturation and cause long-lasting neurobiological changes that ultimately affect the function and behavior of the adult brain. Indeed, emerging evidence from both human and animal studies demonstrates that early-onset marijuana use has long-lasting consequences on cognition; moreover, in humans, this use is associated with a two-fold increase in the risk of developing a psychotic disorder. Here, we review the relationship between cannabinoid exposure during adolescence and the increased risk of neuropsychiatric disorders, focusing on both clinical and animal studies.

Full text available in the link.

Hmm.


 
Alternative Facts
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Come Max, don't you know all sources are biased?


Mad Max | Mythic Invincible!
 
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Come Max, don't you know all sources are biased?
Oh right, my bad...

:P


Azumarill | Mythic Invincible!
 
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isnt this old news?


Mad Max | Mythic Invincible!
 
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isnt this old news?
Well, this was published in November of 2014. Not like...OLD old.


Azumarill | Mythic Invincible!
 
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isnt this old news?
Well, this was published in November of 2014. Not like...OLD old.
i mean, i feel like we've known this for at least a year or so. i wasnt necessarily referring to this specific study, which im sure was meant to act as a followup to previous research to help clear some things up.


Mad Max | Mythic Invincible!
 
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isnt this old news?
Well, this was published in November of 2014. Not like...OLD old.
i mean, i feel like we've known this for at least a year or so. i wasnt necessarily referring to this specific study, which im sure was meant to act as a followup to previous research to help clear some things up.
Perhaps there were others. I can't say I know for sure.


Azumarill | Mythic Invincible!
 
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isnt this old news?
Well, this was published in November of 2014. Not like...OLD old.
i mean, i feel like we've known this for at least a year or so. i wasnt necessarily referring to this specific study, which im sure was meant to act as a followup to previous research to help clear some things up.
Perhaps there were others. I can't say I know for sure.
a brief googling reveals this from march 2014. im sure there's more from before then, too
http://www.npr.org/blogs/health/2014/02/25/282631913/marijuana-may-hurt-the-developing-teen-brain

and some (somewhat understated) research from 2009
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2827693/


some more googling reveals that research really picked up around 2013/2014
Last Edit: January 13, 2015, 07:50:48 PM by Azumarill


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"With the first link, the chain is forged. The first speech censured, the first thought forbidden, the first freedom denied, chains us all irrevocably."
β€”Judge Aaron Satie
β€”β€”Carmen
I don't care if weed gave me cancer, I'd still smoke it.


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I'd rather have 'em smoking weed than getting vehemently drunk.


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I don't care if weed gave me cancer, I'd still smoke it.
it can give you lung cancer

anything you smoke can

but who cares we're all gonna die anyway might as well have some fun before then


🍁 Aria πŸ” | Mythic Inconceivable!
 
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His eyebrows sparkling, his white beard hangs down to his chest. The thatched mats, spread outside his chise, spread softly, his splendid attos. He polishes, cross-legged, his makiri, with his eyes completely absorbed.

He is Ainu.

The god of Ainu Mosir, Ae-Oine Kamuy, descendant of Okiku-Rumi, He perishes, a living corpse. The summers day, the white sunlight, unabrushed, ends simply through his breath alone.
"Long-term use" implies a deal of frequency. Basically, it's saying what most people already assume: occasionally using it won't hurt you, but it's for the best not to become a chronic smoker.


 
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If you're going to let trivial things like that keep you from smoking dank weed you don't deserve to live.
I...didn't say that?


 
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I DONT GIVE A SINGLE -blam!- MOTHER -blam!-ER ITS A MOTHER -blam!-ING FORUM, OH WOW, YOU HAVE THE WORD NINJA BELOW YOUR NAME, HOW MOTHER -blam!-ING COOL, NOT, YOUR ARE NOTHING TO ME BUT A BRAINWASHED PIECE OF SHIT BLOGGER, PEOPLE ONLY LIKE YOU BECAUSE YOU HAVE NINJA BELOW YOUR NAME, SO PLEASE PUNCH YOURAELF IN THE FACE AND STAB YOUR EYE BECAUSE YOU ARE NOTHING BUT A PIECE OF SHIT OF SOCIETY
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Mad Max | Mythic Invincible!
 
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If you're going to let trivial things like that keep you from smoking dank weed you don't deserve to live.
I...didn't say that?
I don't know man I'm getting a pretty strong anti dank vibe here.
I'm mostly in favor of legalizing marijuana across the board. My only hang-up is there's no reliable field test for marijuana use if you get pulled over or something. With alcohol, it effects most people in a similar manner, and on a relatively linear and predictable scale. The same doesn't happen with marijuana use. Once we have something reliable, I'm all for it.

I have no beef with people who want to smoke weed. Many of my friends do. I've done it a handful of times, but I just don't like the feeling of being high.


TheOneTrueDesticle | Heroic Unstoppable!
 
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http://vocaroo.com/i/s03nPj9fDBcN

The Pancakes List:

-Latsu
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Don't let Camnator see this.

I mean, it shouldn't be a problem. I don't think he's ever even stepped foot in Serious.


Mega Sceptile | Heroic Unstoppable!
 
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So THAT'S why Camnator keeps repeating the same jokes over and over again!


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If You Are A False Don't Entry
I get really annoyed at my stoner friends online for smoking that crap as much as they do. My one former friend was 17 years old and she would smoke it every day and always be telling me about their bong hits and shit. Not only is it annoying, but I seriously think that it effects their cognitive function. People always seem a bit slower when they are smoking weed and trying to talk to me. It's like it's harder for them to carry a train of thought. It's a really fucking annoying drug that gets way way way way way too much notoriety among people. I would smoke it, and I would legalize it, but I just think that it's really stupid the way some people treat it.
Last Edit: January 13, 2015, 11:44:00 PM by Loaf


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This is pathetic, Cheat
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If I'm not here, I'm doing photography. Or I'm asleep. Or in lockdown. One of those three, anyway.

The current titlebar/avatar setup is just normal.
I can agree with that.

Makes sense why my crazy roommate would leave stuff everywhere and be completely retarded.

You could seriously get away with calling her stupid and she wouldn't even notice. WHEN SOBER.


Mad Max | Mythic Invincible!
 
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If you're going to let trivial things like that keep you from smoking dank weed you don't deserve to live.
I...didn't say that?
I don't know man I'm getting a pretty strong anti dank vibe here.
I'm mostly in favor of legalizing marijuana across the board. My only hang-up is there's no reliable field test for marijuana use if you get pulled over or something. With alcohol, it effects most people in a similar manner, and on a relatively linear and predictable scale. The same doesn't happen with marijuana use. Once we have something reliable, I'm all for it.

I have no beef with people who want to smoke weed. Many of my friends do. I've done it a handful of times, but I just don't like the feeling of being high.
Uh

I was joking.
...oh...


 
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emigrate or degenerate. the choice is yours
And we smoke substances that turn our lungs into shriveled prunes, drink liquids that kill our braincells, and eat fast food that cakes our heart in grease. If this was a jab at the legality of Marijuana then it isn't a very good one.

I can also find lots of conflicted studies that dispute this, but we aren't even allowed to conduct official studies cause the gubment or something.
Last Edit: January 14, 2015, 10:53:17 AM by Madman Mordo


Mad Max | Mythic Invincible!
 
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If this was a jab at the legality of Marijuana then it isn't a very good one.
It wasn't. Just because I think smoking weed is stupid doesn't mean I think it should be illegal.


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More Than Mortal
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This is the way the world ends. Not with a bang but a whimper.
This is exactly why it should be legalised.


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This is pathetic, Cheat
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More Than Mortal
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This is the way the world ends. Not with a bang but a whimper.
This is exactly why it should be legalised.
Social darwinism?
. . .

No, because you can fucking regulate it when it's legal.