Sort of.In Skyrim I'd keep certain things in chests, like jewels.But everything else would go in a pile outside my house, because there was so much shit I couldn't hope to sell it all.
I need to collect at least one of every item in my inventory, if the game allows you to.If I find a rare item, I will not consume it if it's the only one I have--even if I could really use it.
It's not an RPG unless hoarding items is possible.