http://www.sciencedaily.com/releases/2013/05/130521132122.htm

An attack on glioblastoma brain tumor cells that uses a modified poliovirus is showing encouraging results in an early study to establish the proper dose level, researchers at Duke Cancer Institute report.
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    Glioma

The treatment, developed at Duke and tested in an ongoing phase 1 study, capitalizes on the discovery that cancer cells have an abundance of receptors that work like magnets drawing the poliovirus, which then infects and kills the cells.

The investigational therapy, known as PVSRIPO, uses an engineered form of the virus that is lethal to cancer cells, while harmless to normal cells. Infused directly into the patient's tumor, the virus-based therapy also triggers the body's immune fighters to launch an attack against the infected tumor cells.

Preliminary data, presented at the upcoming 2013 Annual Meeting of the American Society of Clinical Oncology in Chicago, previews the results of seven patients enrolled in the study whose tumors reoccurred despite traditional treatments for glioblastoma multiforme, the most common and aggressive brain tumor.

Of the patients enrolled in the study, three have responded well to the drug. One patient remains disease-free 12 months after treatment, another 11 months post-treatment and the third is disease-free after five months. With traditional treatment, about half of glioblastoma patients see recurrent tumor growth within eight weeks.

Two patients in the study did not fair as well; one had recurrent tumor growth after two months, and another's condition declined after four months. The remaining two patients have been treated in the last three and two months, respectively, and currently remain disease free.

"These early results are intriguing," said Annick Desjardins, M.D., FRCPC, principal investigator and associate professor of medicine at Duke University School of Medicine. "Current therapies for glioblastoma are limited because they cannot cross the blood-brain barrier and often do not specifically attack the tumor. This treatment appears to overcome those problems. We are eager to see additional results as we move forward with our study."

This is pretty interesting. Saw the 60-Minute episode covering this, so far 22 patients have undergone Phase 1 of the clinical trials. 11 of them died, but it was noted despite succumbing to the disease, they lived months longer than averagely estimated for those with recurrent glioblastoma, a major step forward. Even the fact that the first two patients are now considered "cancer free" and have been for several years is a very promising thing in itself, since Phase 1 of a clinical trial is more for determining the proper dose of a treatment and not a determination of effectiveness. This being said, the unusual effectiveness so early in the trials and in Phase 1 has the medical directors very surprised and very optimistic for the future.

Another article on polio therapy:

http://www.forbes.com/sites/davidkroll/2015/03/30/60-minutes-covers-dukes-polio-virus-clinical-trial-against-glioblastoma/

That's how people work. Everyone likes bad news.

I SEE HOW YOU FAGGOTS ARE, YOU ONLY REPLY TO RELIGIOUS OR POLITICALLY CHARGED THREADS YOU FUCKING FAGGOTS. FOR ONCE ONE GOOD THING GETS POSTED IN SERIOUS ABOUT A REVOLUTIONARY STEP IN BATTLING CANCER AND NONE OF YOU FUCKS REPLY LOL ALL YOU CARE ABOUT IS SUFFERING, KILL YOURSELVES

C'mon, these news stories are kind of a dime a dozen. Hopeful cancer cures by using some other deadly illness or something. It's in its first stage and there are really no conclusive results. Add that to the fact that pretty much nobody here has the medical knowledge to comment on it, and this thread was going nowhere, fast.

Quote from: ANGER on April 06, 2015, 01:54:34 AM

I SEE HOW YOU FAGGOTS ARE, YOU ONLY REPLY TO RELIGIOUS OR POLITICALLY CHARGED THREADS YOU FUCKING FAGGOTS. FOR ONCE ONE GOOD THING GETS POSTED IN SERIOUS ABOUT A REVOLUTIONARY STEP IN BATTLING CANCER AND NONE OF YOU FUCKS REPLY LOL ALL YOU CARE ABOUT IS SUFFERING, KILL YOURSELVES

C'mon, these news stories are kind of a dime a dozen. Hopeful cancer cures by using some other deadly illness or something. It's in its first stage and there are really no conclusive results. Add that to the fact that pretty much nobody here has the medical knowledge to comment on it, and this thread was going nowhere, fast.

Dime a dozen? What's the last prominently and (cautiously) promising cancer "cure" you've heard of? Yes, this is in Phase 1, but even the Phase 1 studies have the medical directors, big time global cancer doctors excited, and that's not something you hear very often at all.

Quote from: ANGER on April 06, 2015, 09:11:06 AM

Dime a dozen? What's the last prominently and (cautiously) promising cancer "cure" you've heard of?

Specifically regarding viruses combating cancer? Measles, HIV, and herpes for starters.

Did they produce the same kind of promising results as this has in Phase 1?

Neat.

Quote from: HurtfulTurkey on April 06, 2015, 09:36:08 AM

Quote from: ANGER on April 06, 2015, 09:25:18 AM

Quote from: EasterTurkey on April 06, 2015, 09:24:13 AM

Quote from: ANGER on April 06, 2015, 09:11:06 AM

Dime a dozen? What's the last prominently and (cautiously) promising cancer "cure" you've heard of?

Specifically regarding viruses combating cancer? Measles, HIV, and herpes for starters.

Did they produce the same kind of promising results as this has in Phase 1?

Yes. The point is that there's really not much to discuss here. I read the article, thought it was interesting, then left the thread.

Link results then, I'm curious to see about those.

You're welcome to do your own research into it, but I'm not your personal source of data. I recommend the American Journal of Medicine.