Marijuana is the most widely used illicit drug among adolescents and young adults. Unique cognitive, emotional, and social changes occur during this critical period of development from childhood into adulthood. The adolescent brain is in a state of transition and differs from the adult brain with respect to both anatomy (e.g., neuronal connections and morphology) and neurochemistry (e.g., dopamine, GABA, and glutamate). These changes are thought to support the emergence of adult cerebral processes and behaviors. The endocannabinoid system plays an important role in development by acting on synaptic plasticity, neuronal cell proliferation, migration, and differentiation. Delta-9-tetrahydrocanabinol (THC), the principal psychoactive component in marijuana, acts as a partial agonist of the cannabinoid type 1 receptor (CB1R). Thus, over-activation of the endocannabinoid system by chronic exposure to CB1R agonists (e.g., THC, CP-55,940, and WIN55,212-2) during adolescence can dramatically alter brain maturation and cause long-lasting neurobiological changes that ultimately affect the function and behavior of the adult brain. Indeed, emerging evidence from both human and animal studies demonstrates that early-onset marijuana use has long-lasting consequences on cognition; moreover, in humans, this use is associated with a two-fold increase in the risk of developing a psychotic disorder. Here, we review the relationship between cannabinoid exposure during adolescence and the increased risk of neuropsychiatric disorders, focusing on both clinical and animal studies.
Come Max, don't you know all sources are biased?
isnt this old news?
Quote from: Azumarill on January 13, 2015, 07:40:37 PMisnt this old news?Well, this was published in November of 2014. Not like...OLD old.
Quote from: Mad Max on January 13, 2015, 07:42:28 PMQuote from: Azumarill on January 13, 2015, 07:40:37 PMisnt this old news?Well, this was published in November of 2014. Not like...OLD old.i mean, i feel like we've known this for at least a year or so. i wasnt necessarily referring to this specific study, which im sure was meant to act as a followup to previous research to help clear some things up.
Quote from: Azumarill on January 13, 2015, 07:44:12 PMQuote from: Mad Max on January 13, 2015, 07:42:28 PMQuote from: Azumarill on January 13, 2015, 07:40:37 PMisnt this old news?Well, this was published in November of 2014. Not like...OLD old.i mean, i feel like we've known this for at least a year or so. i wasnt necessarily referring to this specific study, which im sure was meant to act as a followup to previous research to help clear some things up.Perhaps there were others. I can't say I know for sure.
I don't care if weed gave me cancer, I'd still smoke it.
If you're going to let trivial things like that keep you from smoking dank weed you don't deserve to live.
Quote from: Mad Max on January 13, 2015, 09:58:53 PMQuote from: challengerX on January 13, 2015, 08:32:33 PMIf you're going to let trivial things like that keep you from smoking dank weed you don't deserve to live.I...didn't say that?I don't know man I'm getting a pretty strong anti dank vibe here.
Quote from: challengerX on January 13, 2015, 08:32:33 PMIf you're going to let trivial things like that keep you from smoking dank weed you don't deserve to live.I...didn't say that?
Quote from: Mad Max on January 13, 2015, 10:05:26 PMQuote from: challengerX on January 13, 2015, 10:00:00 PMQuote from: Mad Max on January 13, 2015, 09:58:53 PMQuote from: challengerX on January 13, 2015, 08:32:33 PMIf you're going to let trivial things like that keep you from smoking dank weed you don't deserve to live.I...didn't say that?I don't know man I'm getting a pretty strong anti dank vibe here.I'm mostly in favor of legalizing marijuana across the board. My only hang-up is there's no reliable field test for marijuana use if you get pulled over or something. With alcohol, it effects most people in a similar manner, and on a relatively linear and predictable scale. The same doesn't happen with marijuana use. Once we have something reliable, I'm all for it.I have no beef with people who want to smoke weed. Many of my friends do. I've done it a handful of times, but I just don't like the feeling of being high.UhI was joking.
Quote from: challengerX on January 13, 2015, 10:00:00 PMQuote from: Mad Max on January 13, 2015, 09:58:53 PMQuote from: challengerX on January 13, 2015, 08:32:33 PMIf you're going to let trivial things like that keep you from smoking dank weed you don't deserve to live.I...didn't say that?I don't know man I'm getting a pretty strong anti dank vibe here.I'm mostly in favor of legalizing marijuana across the board. My only hang-up is there's no reliable field test for marijuana use if you get pulled over or something. With alcohol, it effects most people in a similar manner, and on a relatively linear and predictable scale. The same doesn't happen with marijuana use. Once we have something reliable, I'm all for it.I have no beef with people who want to smoke weed. Many of my friends do. I've done it a handful of times, but I just don't like the feeling of being high.
If this was a jab at the legality of Marijuana then it isn't a very good one.
Quote from: Meta Cognition on January 14, 2015, 12:23:43 PMThis is exactly why it should be legalised.Social darwinism?
This is exactly why it should be legalised.